Tuberculosis and immune response inflammatory syndrome
نویسندگان
چکیده
منابع مشابه
Immune reconstitution inflammatory syndrome in CNS tuberculosis.
BACKGROUND Immune Reconstitution Inflammatory Syndrome (IRIS), an exaggerated inflammatory response with clinical worsening due to immune recovery during treatment, is rare in the immune-competent population. CASE CHARACTERISTICS A 5-½-year old immune-competent girl with CNS tuberculosis without HIV who developed paradoxical IRIS. OUTCOME Response to supportive care along with Anti-tubercul...
متن کاملAIDS and disseminated tuberculosis after Immune Reconstitution Inflammatory Syndrome.
Fig. 1 – Massive pleural effusion in the right hemithorax, diffuse bilateral micronodular infiltration in both lungs, and hilar lymphadenopathy in thoracic CT. A 29-year-old male patient was admitted at the hospital with complaints of diarrhea and weight loss that had started two months ago. In his physical examination and laboratory tests, HIV positivity was detected (CD4 cell count 175 mL–1, ...
متن کاملParadoxical reactions and immune reconstitution inflammatory syndrome in tuberculosis.
The coalescence of the HIV-1 and tuberculosis (TB) epidemics in Sub-Saharan Africa has had a significant and negative impact on global health. The availability of effective antimicrobial treatment for both HIV-1 (in the form of highly active antiretroviral therapy (HAART)) and TB (with antimycobacterial agents) has the potential to mitigate the associated morbidity and mortality. However, the u...
متن کاملHypercytokinaemia accompanies HIV-tuberculosis immune reconstitution inflammatory syndrome.
Increased access to combination antiretroviral therapy in areas co-endemic for tuberculosis (TB) and HIV-1 infection is associated with an increased incidence of immune reconstitution inflammatory syndrome (TB-IRIS) whose cause is poorly understood. A case-control analysis of pro- and anti-inflammatory cytokines in TB-IRIS patients sampled at clinical presentation, and similar control patients ...
متن کاملCytotoxic Mediators in Paradoxical HIV–Tuberculosis Immune Reconstitution Inflammatory Syndrome
Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) frequently complicates combined antiretroviral therapy and antituberculosis therapy in HIV-1-coinfected tuberculosis patients. The immunopathological mechanisms underlying TB-IRIS are incompletely defined, and improved understanding is required to derive new treatments and to reduce associated morbidity and mortality....
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ژورنال
عنوان ژورنال: Journal of the International AIDS Society
سال: 2013
ISSN: 1758-2652
DOI: 10.7448/ias.16.2.18708